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In the present work we synthesized some novel α, β-unsaturated ketones with an aim to obtain some new potent antibacterial and antioxidant agents. The α, β-unsaturated ketones were synthesized by base catalysed Claisen-Schmidt condensation of ketones having α, α’ hydrogens with various aldehydes. Three new series of α, β-unsaturated ketones were synthesized by reacting γ-t-butylcyclohexanone, γ-phenylcyclohexanone and γ-ethylcyclohexanone with different substituted benzaldehydes. The classes of the synthesized compounds are: α,α’-Bis(substitutedarylidene)-γ-t-butylcyclohexanones[1a-j],α,α’ Bis(substitutedarylidene)-γ-phenylcyclohexanones [2a-h], The formation of the compounds [1a-j] and [2a-h] are indicated by their UV spectra. The functional groups in the compounds [1a-j] and [2a-h] are characterized by their IR spectra.

Plants are one of the most important of medicines. Basil (Ocimum americanum) is one such plant which symbolize all that is extraordinary in nature because the entire whole plant has been used traditional medicine for household remedy against various human from antiquity. The genus O.americanum is known to include species accumulating essential oils. In this study the secondary metabolites of both flowers and leaves of O.americanum which occur in the central Sudan. The proximate analysis to samples showed the percentage of moisture content, total ash, crude fiber and fiber protein of the leave and flowers. The elemental analysis used Atomic Absorption Spectrometer (AAS) and flame emission for Ca, Fe, Na, K, Mg, Pb and Mn plant under study.

Selective estrogen receptor modulators drugs, which exert estrogenic as well as anti-estrogenic actions in a tissue selective manner, are used for the treatment of osteoporosis, breast cancer and with effects on the uterus and vagina that depend on the interaction with the estrogen receptors in target tissues. Due to decline of estrogen levels after menopause, hot flashes and sweating occurred as the part of the menopausal vasomotor symptoms with the estrogen related urogenital atrophy and loss of bone density. Selective estrogen receptor modulators (SERMs) has three compounds Tamoxifen Citrate, Raloxifene, Bazedofene. Tamoxifen acts as selective estrogen receptor modulator or as a partial agonist of the estrogen receptors. It has mixed estrogenic and anti-estrogenic activity with its profile of effects deficiency by tissue.

WHO defines an ADR as, “Any response to a drug which is noxious and unintended, and which occurs at doses normally used in man for prophylaxis, diagnosis, or therapy of disease, or for the modification of physiological function”. A psychosis is a mental disorder characterized by a disconnection from reality. Antipsychotics are the most effective drugs which are used in the psychiatry in the maintenance therapy of mania, psychoses and schizophrenia. The antipsychotics drugs are chemically disparate but have the common property of alleviating the symptoms of organic as well as functional psychosis. But they also have a capacity to cause a wide range of potential adverse drug reactions that can lead to non-compliance that can impair quality of life, may cause the extra pyramidal symptoms which can lead to discontinuation of therapy and in extreme cases it may be fatal. Knowledge of assessment of ADR due to different antipsychotics is necessary. It helps to choose to safe treatment and reduce the risk of occurrence of ADRs by the clinicians.

Health of women is one of society’s most critical issues because women must be physically, mentally and emotionally well before they can devote themselves to serve their families and to consider other important social issues. There are many Gynaecological disorders found in women that needs to be timely diagnosed and cured to avoid major health problems. Common gynaecological disorders most of the females suffer are Usr-e-tams wa Ehtabas-e-tams (Dysmenorrhoea and Ammenorrhea), Kasrat-e-Haiz (Menorrhagia), Sailan-e-reham (Leucorrhoea),Hikkat-ul-Farj (Pruritis vulvae),Warm-e-Farj wa Mehbal (Vulvitis and Vaginitis),Warm-e- Reham (Metritis), PCOD (Polycystic ovarian disease) and Uqr-Banjhpan (Sterility).