volume9issue22023

Research in Pharmacy and Health Sciences, Volume 9, Issue 2: April-June, 2023

1.RECENT DEVELOPMENTS IN THE ANTIMICROBIAL ACTIVITY OF QUINAZOLINE

Shraddha Raj, Rahul Pandey*, Ganesh Kumar, Saurabh Kumar, Pratyush Kumar, Chirag Chandel

DOI: https://doi.org/10.32464/RPHS.2023.v09i02.01

Abstract
Quinazoline derivatives have gained increasing attention in the synthesis and bioactivities study due to their substantial biological activities. To develop antibacterial agents that are more effective, Quinazoline is frequently tested for studies. Lead compounds containing Quinazoline with significant antimicrobial activity have been identified in the recent years. The emergence of drug-resistant microbial pathogens has spurred intensive research on novel antimicrobial agents. Quinazoline derivatives have shown promising potential as antimicrobial agents due to their diverse chemical structures and pharmacological activities. This review critically examines the recent developments in the antimicrobial activity of quinazoline compounds. Additionally, the potential challenges and future directions in the development of quinazoline-based antimicrobials are explored. The comprehensive analysis of recent advancements in the field of quinazoline antimicrobial research presented in this review will aid in the design of more effective and targeted therapeutic strategies against drug-resistant pathogens.

Keywords: Buccal quinazoline, antimicrobials, anticancer, quinazolin-3,4-dione, quinazolinone, antibiotic resistance…..